Enamelate

Smart minerals. Stronger teeth.

BiPhasic-ACP™ technology for rapid, natural tooth remineralization.

The Global Dental Challenge

2.8 Billion People Have Untreated Cavities

Dental caries affect nearly half the global population, creating a $544 billion annual economic burden. In Canada alone, 96% of adults have experienced tooth decay.

Traditional dentistry is reactive, drilling and filling after damage becomes irreversible. But there's a better way...

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Healing Teeth Naturally

Many people don't know that teeth can heal themselves. Acid damage and early-stage cavities are reversible through the natural process of remineralization, where trace levels of minerals dissolved in saliva can rebuild the first signs of damaged tooth enamel.

But nature needs help. Natural enamel remineralization is significantly limited by the low-levels of bioactive minerals in saliva. Current remineralization products are either too slow, contain concerning ingredients, or become ineffective before they reach your teeth.

No drilling required - natural tooth healing illustration

Enamelate has solved this problem with BiPhasic-ACP™, the first truly bistable remineralization technology that's stable in its active form on the shelf, while remaining rapidly bioactive when it reaches your mouth. Unlike casein-stabilized formulations or pre-formed nano-hydroxyapatite products, BiPhasic-ACP™ combines the rapid bioactivity of amorphous calcium phosphate with unprecedented shelf stability and allergen-free formulation. By delivering the same mineral building blocks nature uses to form enamel, we've created a biomimetic solution that works with your body's natural enamel healing mechanisms.

Why BiPhasic-ACP™ is Different

Rapid Action

Delivers measurable remineralization in minutes, not months. Our technology works with your body's natural healing process, just faster.

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Clean Label

No milk proteins, no harsh preservatives, no fluoride. Just pure, biocompatible minerals that match natural enamel composition by ~95%.

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Scientifically Validated

In vitro testing demonstrates superior performance compared to existing non-prescription technologies. Patent-pending biomimetic innovation backed by rigorous research.

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Shelf-Stable

Remains stable for months at room temperature, yet transforms into bioactive nano-hydroxyapatite within moments of contacting saliva.

The Science of Tooth Healing

How Natural Remineralization Works

  • Acid attacks tooth enamel (from food, bacteria).
  • Minerals leach out of enamel, creating micro-damage.
  • Saliva delivers minerals as amorphous calcium phosphate (ACP).
  • ACP crystalizes as nano-HA, repairing a small amount of damage.
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Why Natural Healing Often Fails

  • Saliva doesn't provide enough minerals (ACP).
  • Natural process is too slow compared to rate of damage.
  • By the time you notice damage, it's often too advanced.
  • Result: cavity progresses to a point of no return.
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💡 The opportunity: Technology can enhance and accelerate this natural healing process.

BiPhasic-ACP™: Smart Minerals That Transform on Demand

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Stable on the Shelf

BiPhasic-ACP™ remains stable in storage as a preserved, bioactive amorphous calcium phosphate molecule.

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Contact with Saliva

Rehydration triggers a rapid phase transformation from ACP to nano-HA crystals on tooth surfaces.

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Natural Integration

The bioactive nature of ACP means the newly formed nano-HA bonds with enamel, restoring strength.

This intelligent transformation gives BiPhasic-ACP™ advantages no other non-prescription technology can match, combining the rapid action of amorphous calcium phosphate with the shelf stability required for commercial products.

Proven Performance

BiPhasic-ACP™ delivers demonstrated performance across all metrics, with rapid remineralization in 6 x 1 hr applications (or less) and superior performance to top competitors studied under the same conditions. In direct comparative testing against leading casein-based ACP formulations, BiPhasic-ACP™ demonstrated superior remineralization capacity while eliminating common allergen concerns and formulation instability. Results validated through comprehensive in vitro analysis including SEM surface morphology, EDS chemical characterization, and ongoing microindentation hardness testing.

SEM analysis of enamel remineralized by BiPhasic-ACP

Enamel remineralized by BiPhasic-ACP™ shows near-complete restoration of acid-damaged enamel structure in 6 x 1 hr applications (or less).

Bioactivity confirmed: Surface chemistry and morphology of acid-damaged enamel restored to healthy range in just 6 x 1 hr applications (or less).

B2B Licensing for Maximum Impact

We partner with established oral care brands and dental professionals to bring BiPhasic-ACP™ to market through a licensing model.

This approach allows us to scale rapidly while focusing on what we do best: advancing remineralization science.

Streamlined Regulatory Pathway

BiPhasic-ACP™ qualifies for Natural Health Product (NHP) licensing in Canada, offering licensing partners a faster, more cost-effective path to market compared to prescription drug approval. NHP status enables distribution through mass-market retail channels while maintaining regulatory credibility.

Interested in licensing BiPhasic-ACP™ for your product line?

Currently accepting expressions of interest for 2026 partnership opportunities.

Contact Us

Expert Leadership in Biomaterials Science

Dr. Alexis Pietak

Alexis Pietak, PhD

Founder, President & Lead Scientist

Dr. Pietak brings over a decade of specialized expertise in calcium phosphate biomaterials to Enamelate. With a PhD focused on these materials and extensive experience in both academic and corporate research settings, she is a published expert in biomineralization and calcium phosphate biomaterials.

Her deep understanding of how minerals interact with biological systems led to the breakthrough innovations behind BiPhasic-ACP™. Dr. Pietak's vision is to make rapid, safe, natural tooth remineralization accessible to millions worldwide.

Strategic Partners & Advisors

Queen's Partnerships & Innovation

Providing IP strategy, business mentorship, and commercialization support through the FedDev Ontario program.

Academic Collaborations

Technical and experimental services through partnerships with Canadian research universities.

Join Us in Transforming Oral Health

We're actively seeking licensing partners and strategic investors who share our vision of making tooth remineralization mainstream.

Get in Touch

Interested in investment opportunities, sales, licensing, or research collaborations? We'd love to hear from you.